Over the past four-plus years, the proprietary computer model has generated a stunning profit of over $4,200 for $100 players on its top-rated college football picks against the spread.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Will the Hurricanes hang close and cover the spread, or should you look elsewhere for the best value college football bets? Before making any Week 6 college football picks on those games or others, be sure to see the latest college football predictions from SportsLine's proven model. The Tigers are 10-0 in their last 10 home games, while Miami is 5-1 against the spread in its last six games against ACC opponents.

The Week 6 college football odds from William Hill list Clemson as a 15-point favorite at home against Miami. However, the Tigers are just 1-4 against the spread in their last five outings. Clemson enters Saturday night's showdown against the Hurricanes having won 19 of its last 20 games. The Week 6 college football schedule features a number of intriguing top-25 matchups, including No.

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